Yuki was born in Japan but raised in West Germany for most of her childhood. Her father was a big fan of classical and opera music and always desired for Yuki to play the piano for him. Yuki eventually gained a love for music and a love for the piano.
Yuki started out as an SE programmer, but changed to music in 1992. She made her grand debut with a female trio called "See-Saw." In the years to come the group released six singles and two albums.
Yuki then went on to work on her solo career composing for artists and some TV, films, and games, such as Blood: The Last Vampire in 2001, and Xenosaga II and III.
In 2001 Yuki's claim to fame came with the release of the anime "NOIR." The soundtrack sold 50,000 copies. In 2002 she was brought on to project .hack to write the score to .hack//SIGN, along with volcalist Chiaki Ishikawa and
New York singer Emily Bindiger. Shortly after Yuki comprised an album of original and complied songs known as Fiction, working again with Emily Bindiger as well as Xenosaga vocalist Deb Lyons.
Yuki's other well known works were for Mobile Suite Gundam Seed, which hit 5th on the Oricon Charts its first week, and selling over 200,000 copies.
Yuki has also become known for her work on CLAMP's Tsubasa Chronicle series movie and OAV's.
In 2007, Yuki formed the band Kalafina, with two partners from the FictionJunction project, Wakana Ōtaki and Keiko Kubota, mainly to perform for the anime Kara no Kyōkai; but the band continues active as of this writing.